In order to complete the full-face automatic processing and production of the aero-engine’s whole leaf disc tip, blade body, edge, blade root and runner surface, it is necessary to integrate the aero-engine blisk grinding system. However, the processing equipment such as the robot grinding mechanism, the numerical control rotary table, the blue light detector, and the digital silo are isolated from each other to form an automated island phenomenon, which results in the data collected by each device cannot be uploaded and downlinked in time and effectively, and the integration of management and control cannot be realized. Therefore, this paper proposes a system integration scheme for the aero-engine blisk robot grinding method. Firstly, based on the analysis of the existing process, the integrated construction target and overall framework of the aeroplane blisk grinding system are proposed. Then, the integration of the whole system information is realized through the industrial Ethernet and OPC technology. Finally, the navigation is carried out. The leaf disc was experimentally verified by the system integration scheme. The experimental results show that the Blisk after the grinding by the robot has high surface integrity.