Abstract:To solve the machining problems of large-scale precise casting titanium alloy components, such as complicated manufacturing processing, poor stiffness, hard-controlled deformation, and difficult processing features, the article finds out an efficient solving processing, which has been implemented in real manufacturing project, from fixing equipment, location technology, deformation control, allowance measurement, cutting tools, cutting parameters, manufacturing strategy, etc. This process lays a solid foundation for the machining of precise casting titanium alloy components and similar structural parts on aircraft, and has good popularization and practical value.