GH710 is an important material with high strength, high temperature resistance and poor cutting performance, which make it difficult to guarantee the machining accuracy of blisk blade. According to the characteristics of GH710 blisk, CBN electroplated grinding wheel was presented. Precision grinding of GH710 blisk blade was realized based on optimization of grinding parameters and process, and verification tests were performed. The results show that the machining accuracy of GH710 blisk blade can be realized utilizing CBN electroplated grinding wheel and symmetrical plunge grinding, the profile error of blade surface is below 0.04mm and the requirement of wheel lifetime and grinding efficiency can be satisfied.