Titanium alloy sheet products are widely used in aviation, aerospace, marine, shipbuilding and other national defense fields. The manufacturing technology of titanium alloy sheet is still not fully matured though it has been continuously broken through and improved over the years. In this paper, the status of titanium alloy  sheet manufacturing technology is summarized. The rolling process of sheet metal is introduced, the progress and problems are analyzed emphatically. The rolling technology and microstructure characteristics of different titanium alloys (α titanium alloy, α + β titanium alloy and β titanium alloy) are compared by reviewing the process of cold rolling and pack ply-rolling. The key process and common problems in the rolling process of titanium alloy sheet are clarified and specific solutions are put forward. Finally, the research focus and development direction of titanium alloy sheet rolling technology in China are prospected.