Carbon fiber reinforced resin matrix composites (CFRP) and titanium alloys (Ti6Al4V) are widelyfavored in the aviation field for their excellent high specific strength, high specific stiffness, excellent corrosion resistance and thermal shock resistance. However, the significant mechanical properties differences between the two materials often lead to poor machining quality and increase tool wear during the process of making holes in composite/titanium composites. This paper summarizes the research progress of cutting parameters, advanced tool design and cutting environment at home and abroad. In view of the fact that vibration perforation as an advanced machining mode has achieved remarkable technological results in complex/titanium laminated structure perforation in recent years, the key technical problems such as cutting force, cutting heat, hole quality and tool wear in complex/titanium laminated structure ultrasonic and low frequency vibration perforation are analyzed in detail. The new fine and strong integrated wave ultrasonic hole making technology is summarized, and the development direction of future research is prospected. The results of this study will provide an important technical reference for high quality and efficient pore preparation of composite/titanium laminated structures.