The aero-engine pipeline system is an important external accessory system to ensure the normal operation of an aero-engine. To improve the efficiency and quality of aero-engine pipeline design, this study analyzes the composition of the model based definition (MBD) dataset and summarizes the design experience and knowledge of designers, and proposes a rapid design method for aero-engine pipeline systems. This method is based on design criteria for pipelinerelated components accessory definition, layout, and laying. Based on the integration of KBE and MBD technologies, the aero-engine pipeline design system is developed through secondary development on the NX and Teamcenter software platforms. The system constructs various databases, model libraries, and knowledge bases, embeds design rules and standards into the process, achieves the management and sharing of pipeline data, and achieves the goal of quickly and intelligently designing aero-engine pipelines.