In order to improve the effi ciency of the missile rapid design and reduce the workload, VC++6.0 is taken as the development environment and Pro/E based on skeleton model’s parametrization modelling, variable and single database is made fully use of to research Pro/E secondary development technology based on Pro/TOOLKIT asynchronous mode. The data communication and sharing between application software and Pro/E is realized to ensure the rapid and automatic update of aircraft appearance and its related parameters and then to drive the automatic analysis of all subjects. Finally, and example is given to verify the validity of the method and the result shows that this method is feasible.