In recent years, high-entropy alloys (HEAs) have attracted extensive attention of researchers because of their unique design concept and excellent properties with multiple principal components. Laser additive manufacturing (LAM) can produce HEAs with ultrafine grain and multi-scale structure, accompanied with excellent mechanical properties. Moreover, the doping of interstitial atoms and the addition of reinforced particles are helpful to further improve the strengt and plasticity of the alloy. It also has broad application prospects in aerospace high-performance structural materials and other fields. In this review, the principles and characteristics of selective laser melting and laser directed energy deposition are introduced firstly. Then, the effects of interstitial atoms (C, B, N) and reinforced particles on the microstructure and mechanical properties of HEAs fabricated by LAM are summarized. Additionally, the strengthening and plasticizing mechanism of each interstitial atom and reinforced particle is analyzed. Finally, the future development trend of LAM highperformance HEAs is prospected.