As a critical material for high-end equipment parts like aero-engines, titanium alloy has good high specific strength, excellent corrosion resistance and super fracture toughness and fatigue performance. As a typical aerospace difficult-to-machine material, the surface integrity of the titanium alloy during the manufacturing process has a crucial impact on its service performance and reliability. On this basis, the research advances on the current research of surface integrity in the titanium alloy manufacturing process are reviewed from the four technological perspectives of cutting, grinding, composite processing and non-traditional machining. Finally, the prospect of future research on cutting, grinding, composite processing and non-traditional machining technology of titanium alloy are prospected.