The composite fuselage is one of the important structures of the new large commercial aircraft. The manufacturing process directly affects the product quality consistency, production capacity, cost, etc. The traditional manual-based manufacturing technology cannot meet the current requirements. In order to verify the automatic forming process of the large-size composite hat-section stringer reinforced panel, a multi-faceted research and verification were carried out, through the technologies of ATL, AFP, the laminated slip, the stringer positioning. The process of automatic forming and other processes has completed the manufacture of the large panel. Studies have shown that the selected panel manufacturing process technology has low risk and high quality consistency, which provides the basis for the automated manufacturing of large-size panel.