The microstructure and mechanical properties of forge + “wire arc additive manufacturing” (WAAM) hybrid manufactured TC11 titanium alloys were investigated by microscope observation, tensile test, SEM observation, microhardness measurement and statistical analysis in this paper. The results show that the hybrid manufactured samples can be divided into three parts: the WAAM region, the heat-affected region, and the forged region according to the structural characteristics. “Elongated equiaxed grains–fine equiaxed grains–columnar grains” distribution characteristic is presented from forging region to WAAM region in both as-deposited and heat-treated samples. The as-deposited microstructure changes from thick Widmanstatten structure in the forged region to fine basketweave in the WAAM region. After double annealing, basketweave transforms into a bimodal structure caused by the recrystallization in the forged region. The microstructure in the WAAM region remains basketweave with larger platelet α. The results of the mechanical properties test show that all fractures occur in the WAAM region because of the lower strength caused by dislocation and grain boundary. The comprehensive mechanical properties of hybrid manufactured TC11 samples are between WAAM samples and forged samples, which show the characteristics of low strength and high plasticity.