This essay studies the layout simulation evaluation technology of aeronautical composite production line, and constructs the digital model of aviation composite material process flow and production line layout. Based on actual projects of aeronautical composite materials digital production line, the simulation modeling and simulation experiment of the process layout of composite production line are completed. Through simulation technology, the process layout design of composite material production line has been quantitatively analyzed and demonstrated, so as to guide the instructand operation of composite production line.